MANU® DETAILED INFORMATION

MANU® is an innovative, dynamic handbrace used to treat the symptoms of the Carpal Tunnel Syndrome (CTS). Clinical trials have shown that it is very effective in reducing, and in some cases  even eliminating the pain associated with CTS. The structure and the components were carefully designed to guarantee maximum comfort. MANU® need only to be worn at night and can be removed in the morning.

All the external components of the MANU® are lined with a soft material called Lycra (80% polyamide, 20% elastomer) which does not irritate the skin and allows it to breathe.

The effectiveness of this device lies in the fact that a moderate grip of distal extremities of the metacarpal bones (from the second to the fifth) and the concurrent extension of the third and fourth fingers relieve paresthesia and pain in the Carpal Tunnel Syndrome (Manente et al., Muscle & Nerve, 1999 and 2001).

A month-long study carried out in 80 patients who had a clinical and electroneurographic diagnosis of CTS. 40 patients wore MANU® at night and the other 40 served as controls. The results were measured by the Levine Scale and the Subjects Global Impression of Change Questionnaire.

In the group who wore MANU®, all patients experienced improvement in their symptoms and the average score on the Levine Scale went from 2.31 (S.D. 0.6) at baseline to 1.50 (S.D. O.5) at study completion (p<0.001); 26 patients (65%) reported remarkable improvement or even complete absence of symptoms in some cases, while 14 patients (35%) reported some improvement. With regard to neurophysiological parameters, the treated patients showed an increase (p=0.05) in the range of their SAPS (Simplified Acute Physiology Score).

In the control group the average score on the Levine Scale was 2.39 (S.D. 0.6) at baseline and 2.32 (S.D. 0.6) at study completion (p=0.6); 1 patient (2.5%) reported a pronounced improvement, 9 patients (22.5%) showed  some improvement and 30 patients (75%) saw no change whatsoever in their symptoms.

A multivariate statistical analysis showed a significant difference (p<0.001)between the two groups in favour of those who wore the MANU® handbrace. Furthermore, these patients reported no discomfort or side effects associated with its use.

For further studies...     

Although the Manu device is intended for home use, it should be used under the guidance of a Healthcare Professional.